What Is Guided Tissue Regeneration?

Guided tissue regeneration (GTR) is an advanced periodontal procedure that encourages your body to regrow bone and tissue destroyed by periodontal disease. Using biocompatible barrier membranes and grafting materials, GTR directs the growth of new bone and connective tissue at sites where they have been lost.
This procedure is distinct from guided bone regeneration (GBR), which focuses specifically on rebuilding bone for implant placement. GTR addresses the full periodontal attachment apparatus — bone, ligament, and cementum — with the goal of restoring the natural support structures around your teeth.
When Is GTR Recommended?
GTR is most effective for treating specific types of periodontal bone defects, particularly vertical or intrabony defects where bone has been lost along one side of a tooth root. It may be recommended when:
- Periodontal disease has caused deep bone defects around teeth
- Conventional periodontal surgery alone cannot adequately restore lost bone
- There is a favorable defect morphology (narrow, deep, contained defects respond best)
- The patient is committed to excellent oral hygiene and follow-up care
How Does Guided Tissue Regeneration Work?

The Challenge
After periodontal surgery removes diseased tissue, the body naturally fills the space with fast-growing gum tissue rather than the slower-growing bone and ligament fibers. This results in a long pocket of soft tissue where bone should be — the tooth remains unsupported.
The Solution
A biocompatible membrane is placed between the gum tissue and the bone defect, acting as a physical barrier. This membrane prevents fast-growing gum cells from invading the space while allowing the slower bone and periodontal ligament cells time to regenerate. Bone grafting material may be placed beneath the membrane to scaffold new bone growth.
Healing and Results
Over several months, new bone and attachment fibers grow into the defect site. Depending on the membrane type used (resorbable or non-resorbable), a second minor procedure may be needed to remove the membrane. The result is measurable new bone and periodontal attachment — allowing teeth that might otherwise be lost to be preserved.
What to Expect During Treatment

GTR is performed under local anesthesia with sedation available for your comfort. The procedure typically takes 1 to 2 hours depending on the number of sites treated. Most patients can return to normal activities within a few days, with full bone maturation occurring over 6 to 12 months.
Post-operative care includes a modified oral hygiene routine, prescribed medications, and regular follow-up visits to monitor healing and tissue regeneration.
Is GTR Right for You?
Not every periodontal defect is a candidate for guided tissue regeneration. Dr. Cherry will perform a thorough evaluation including periodontal probing and imaging to determine whether GTR can predictably regenerate bone at your specific sites. Contact Foundation Implants & Periodontics to schedule your consultation.